Reduced adhesion of macrophages on anodized titanium with select nanotube surface features

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Reduced adhesion of macrophages on anodized titanium with select nanotube surface features

One of the important prerequisites for a successful orthopedic implant apart from being osteoconductive is the elicitation of a favorable immune response that does not lead to the rejection of the implant by the host tissue. Anodization is one of the simplest surface modification processes used to create nanotextured and nanotubular features on metal oxides which has been shown to improve bone ...

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One approach to improve biological properties of current titanium and CoCrMo implant is to mimic the nanostructures of bone. Surface modification via anodization is popular to create such nanometer surface features on these metallic implants. The objective of the present study was to anodize titanium and CoCrMo and then determine osteoblast adhesion on such materials. Hydrofluoric acid was used...

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Surface characteristics and bioactivity of an anodized titanium surface

PURPOSE The aim of this study was to evaluate the surface properties and biological response of an anodized titanium surface by cell proliferation and alkaline phosphatase activity analysis. METHODS Commercial pure titanium (Ti) disks were prepared. The samples were divided into an untreated machined Ti group and anodized Ti group. The anodization of cp-Ti was formed using a constant voltage ...

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Enhanced osteoblast adhesion to drug-coated anodized nanotubular titanium surfaces

Current orthopedic implants have functional lifetimes of only 10-15 years due to a variety of reasons including infection, extensive inflammation, and overall poor osseointegration (or a lack of prolonged bonding of the implant to juxtaposed bone). To improve properties of titanium for orthopedic applications, this study anodized and subsequently coated titanium with drugs known to reduce infec...

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The anodization of titanium involves the formation of a thin, dense and compact, oxide layer. In this process the rutile structure of the original titanium oxide is converted into an anatase structure. It is this anatase structure and how it influences the bonding properties of the sol gel coating of hydroxyapatite (HAp) was the main aim of this research project. "he titanium samples were anodi...

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ژورنال

عنوان ژورنال: International Journal of Nanomedicine

سال: 2011

ISSN: 1178-2013

DOI: 10.2147/ijn.s22763